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Mushrooms are known to be good sources of polysaccharides and phenolic compounds as illustrated in the following figure. A large number of studies have investigated the relationship between phenolics and the antioxidant activity of mushrooms including Agaricus blazei ( Tago et al. 2005 ), Poria cocos ( Gao et al. 2007 ), Ganoderma lucidum ( Miao et al. 2009 ), and Hericium erinaceus ( Okumura et al. 2008, Chen et al. 2009, and Zhu et al. 2009 ). Phenolic compounds and flavonoids are the most abundant groups of secondary metabolites found in medicinal mushrooms. Phenolic compounds contain an aromatic ring with one or more hydroxyl substituents as one of their basic structures. The majority of phenolic compounds found in edible and medicinal mushrooms, such as Hericium erinaceus and Ganoderma lucidum contain one or more hydroxyl groups and have been found to exhibit antioxidant activity ( Okumura et al. 2008 ). These compounds also possess cytotoxic, anti-allergy, antibacterial, anti-inflammatory and antifungal properties ( Okumura et al. 2008 ; Choi et al. 2010 ; Okumura et al. 2009 ). More importantly, the antioxidant activity of mushrooms is closely associated with the phenolic content. Although the phenolic content in mushrooms can vary significantly depending on species, growth conditions and genotype, the phenolic content of edible mushrooms usually ranges from 5.0 to 15.0% dry weight ( Okumura et al. 2008 ). The phenolic content in Hericium erinaceus and Ganoderma lucidum has been reported to be higher than other mushrooms, up to 4.0% and 4.5% dry weight, respectively ( Okumura et al. 2008 ).

joke of the day: tired of the harsh rules of your school, you decided to teach the headmaster a lesson. to do this, you put a cannon on the stairs leading to his office. the headmaster, when he noticed this, immediately sent the head of the school to your house. he thought that you were a nasty little boy who was trying to cause trouble for him. he was busy with his maths homework. your math teacher, who knew that you were innocent, called the police to come and arrest you for trespassing. the police came and found the cannon on the stairs. they also found the headmaster’s head broken into pieces. you were immediately arrested. the police took you to the station, where you had to sign your life away in an official document which now listed your permanent address as the police station. you never saw your parents again. footsteps sound of black cat is coming closer. try to avoid cat, a cute black cat with a purple paw! will you wake up? now you’ll hear cat’s footsteps! will you lose consciousness like in sleepy hollow? i will hear the footsteps of the cat near you. you’ll hear it again, but it will get closer. you still don’t know why cats wander around at night. maybe it will be a good night for you. it doesn’t matter. it will catch you, and your life is over. further evidence suggests that the active ingredient in g. lucidum is the polysaccharide. a unique association of polysaccharides with polypeptides has been reported. the protein fraction of the g. lucidum polysaccharide also induces cell cycle arrest in g0/g1 phase, apoptosis, and caspase activation. recently, liu et al. (2009) suggested the role of tumor necrosis factor-related apoptosis-inducing ligand (trail) in g. lucidum-induced apoptosis. 5ec8ef588b


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